SAFETY TEST
| Primary Skin Irritation test | |
|---|---|
Content |
Apply the test product for 24 hours with closed patch, and the skin irritation is evaluated 1 hour and 24 hours after removal of the patch. |
Number of test participants |
30 |
Period |
3 days |
Evaluation |
Visual evaluation |
| Primary Skin Irritation test for sensitive skin | |
|---|---|
Content |
For sensitive skin, Apply the test product for 24 hours with closed patch, and the skin irritation is evaluated 1 hour and 24 hours after removal of the patch. |
Number of test participants |
30 |
Period |
3 days |
Evaluation |
Visual evaluation |
| Human repeat insult patch test | |
|---|---|
Content |
Apply the test product 9 times with closed patche for 3 weeks. Skin irritation evaluation at each patch removal. |
Number of test participants |
30 |
Period |
3 weeks |
Evaluation |
Visual evaluation |
| Human repeat insult patch test and skin sensitization test | |
|---|---|
Content |
1. Induction phase : Apply the test product repeatly with closed patch (for 3 weeks) 2. Resting period (for 2 weeks) 3. Challenge phase : evaluation skin irritation after apply the test product for 48hours with closed patch ( for 1 weeks ) |
Number of test participants |
30 |
Period |
6 weeks |
Evaluation |
Visual evaluation |
| Eye irritation test | |
|---|---|
Content |
Eye evaluation of ophthalmologists |
Number of test participants |
30 |
Period |
once or N weeks |
Evaluation |
Visual evaluation survey evaluation |
| Stimulation | |
|---|---|
Content |
Visual evaluation & survey evaluation after use of test product |
Number of test participants |
n |
Period |
once or N weeks |
Evaluation |
Visual evaluation survey evaluation |
| Test | Content | Number of test participants | Period | Evaluation |
|---|---|---|---|---|
|
Primary Skin Irritation test |
Apply the test product for 24 hours with closed patch, and the skin irritation is evaluated 1 hour and 24 hours after removal of the patch. | 30 | 3 days | Visual evaluation |
|
Primary Skin Irritation test for sensitive skin |
For sensitive skin, Apply the test product for 24 hours with closed patch, and the skin irritation is evaluated 1 hour and 24 hours after removal of the patch. | 30 | 3 days | Visual evaluation |
|
Human repeat insult patch test |
Apply the test product 9 times with closed patche for 3 weeks. Skin irritation evaluation at each patch removal. | 30 | 3 weeks | Visual evaluation |
|
Human repeat insult patch test and skin sensitization test |
1. Induction phase : Apply the test product repeatly with closed patch (for 3 weeks) 2. Resting period (for 2 weeks) 3. Challenge phase : evaluation skin irritation after apply the test product for 48hours with closed patch ( for 1 weeks ) |
30 | 6 weeks | Visual evaluation |
|
Eye irritation test |
Eye evaluation of ophthalmologists | 30 | once or N weeks | Visual evaluation survey evaluation |
|
Stimulation |
Visual evaluation & survey evaluation after use of test product | n | once or N weeks | Visual evaluation survey evaluation |
| Primary Skin Irritation test | |
|---|---|
Content |
Apply the test product for 24 hours with closed patch, and the skin irritation is evaluated 1 hour and 24 hours after removal of the patch. |
Number of test participants |
30 |
Period |
3 days |
Evaluation |
Visual evaluation |
| Test | Content | Number of test participants | Period | Evaluation |
|---|---|---|---|---|
|
Primary Skin Irritation test |
Apply the test product for 24 hours with closed patch, and the skin irritation is evaluated 1 hour and 24 hours after removal of the patch. | 30 | 3 days | Visual evaluation |
| Primary Skin Irritation test for sensitive skin | |
|---|---|
Content |
For sensitive skin, Apply the test product for 24 hours with closed patch, and the skin irritation is evaluated 1 hour and 24 hours after removal of the patch. |
Number of test participants |
30 |
Period |
3 days |
Evaluation |
Visual evaluation |
| Test | Content | Number of test participants | Period | Evaluation |
|---|---|---|---|---|
|
Primary Skin Irritation test for sensitive skin |
For sensitive skin, Apply the test product for 24 hours with closed patch, and the skin irritation is evaluated 1 hour and 24 hours after removal of the patch. | 30 | 3 days | Visual evaluation |
| Human repeat insult patch test | |
|---|---|
Content |
Apply the test product 9 times with closed patche for 3 weeks. Skin irritation evaluation at each patch removal. |
Number of test participants |
30 |
Period |
3 weeks |
Evaluation |
Visual evaluation |
| Test | Content | Number of test participants | Period | Evaluation |
|---|---|---|---|---|
|
Human repeat insult patch test |
Apply the test product 9 times with closed patche for 3 weeks. Skin irritation evaluation at each patch removal. | 30 | 3 weeks | Visual evaluation |
| Human repeat insult patch test and skin sensitization test | |
|---|---|
Content |
1. Induction phase : Apply the test product repeatly with closed patch (for 3 weeks) 2. Resting period (for 2 weeks) 3. Challenge phase : evaluation skin irritation after apply the test product for 48hours with closed patch ( for 1 weeks ) |
Number of test participants |
30 |
Period |
6 weeks |
Evaluation |
Visual evaluation |
| Test | Content | Number of test participants | Period | Evaluation |
|---|---|---|---|---|
|
Human repeat insult patch test and skin sensitization test |
1. Induction phase : Apply the test product repeatly with closed patch (for 3 weeks) 2. Resting period (for 2 weeks) 3. Challenge phase : evaluation skin irritation after apply the test product for 48hours with closed patch ( for 1 weeks ) |
30 | 6 weeks | Visual evaluation |
| Eye irritation test | |
|---|---|
Content |
Eye evaluation of ophthalmologists |
Number of test participants |
30 |
Period |
once or N weeks |
Evaluation |
Visual evaluation survey evaluation |
| Test | Content | Number of test participants | Period | Evaluation |
|---|---|---|---|---|
|
Eye irritation test |
Eye evaluation of ophthalmologists | 30 | once or N weeks | Visual evaluation survey evaluation |
| Stimulation | |
|---|---|
Content |
Visual evaluation & survey evaluation after use of test product |
Number of test participants |
n |
Period |
once or N weeks |
Evaluation |
Visual evaluation survey evaluation |
| Test | Content | Number of test participants | Period | Evaluation |
|---|---|---|---|---|
|
Stimulation |
Visual evaluation & survey evaluation after use of test product | n | once or N weeks | Visual evaluation survey evaluation |